Last edited by Shagar
Thursday, August 6, 2020 | History

3 edition of The chemical biology of DNA damage found in the catalog.

The chemical biology of DNA damage

Nicholas E. Geacintov

The chemical biology of DNA damage

by Nicholas E. Geacintov

  • 137 Want to read
  • 23 Currently reading

Published by Wiley-VCH in Weinheim .
Written in English

    Subjects:
  • DNA damage,
  • DNA Damage,
  • DNS-Schädigung,
  • Physiology,
  • Science

  • About the Edition

    A modern reference on a key topic in biochemical toxicology that reaches out into molecular biology, molecular medicine and environmental science, The Chemical Biology of DNA Damage covers basic concepts as well as the analysis and prediction of genotoxicty at the molecular level.

    Edition Notes

    Includes bibliographical references and index.

    Statementedited by Nicholas E. Geacintov, Suse Broyde
    Classifications
    LC ClassificationsQH465.A1 C42 2010
    The Physical Object
    Paginationxxii, 449 p. :
    Number of Pages449
    ID Numbers
    Open LibraryOL25309096M
    ISBN 103527322957
    ISBN 109783527322954
    LC Control Number2012382036
    OCLC/WorldCa619226558

    DNA Damage, arising from both endogenous and exogenous chemical insults, is believed to represent an initiating step in chemical carcinogenesis. Considerable data exist with regard how specific DNA adducts perturb its structure, and how these structural perturbations interfere with the biological processing of DNA [ 1 ].   Histone H3 serine 10 is found to be the major chromatin acceptor residue for DNA damage–induced ADP-ribosylation and is blocked by specific acetylation sites on PARP1 and/or H3.

    where The Chemical Biology of DNA Damage John Wiley & Sons, When helicopter pilot Jon Black crashes into a Cambodian jungle, his search for escape leads him to a new world filled with strange creatures, danger, and love. Carcinogen, any of a number of agents that can cause cancer in humans. They can be divided into three major categories: chemical carcinogens (including those from biological sources), physical carcinogens, and oncogenic (cancer-causing) viruses. Most carcinogens, singly or in combination, produce.

    CHEMICAL BIOLOGY. Chemistry of DNA Damage Repair. Erin J. Heenan and Aziz Sancar, university of North Carolina School of Medicine, Chapel Hill, North Carolina. doi: /wecb DNA repair is the elimination of covalent DNA modifications and the correction of base mismatches. Scope. RSC Chemical Biology is a gold open access journal dedicated to publishing and disseminating the most exceptionally significant, breakthrough research and high quality reviews at the interface of chemistry and biology. All published articles must be of significant general interest to the broad chemical biology community. We welcome contributions from across the breadth of chemical.


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The chemical biology of DNA damage by Nicholas E. Geacintov Download PDF EPUB FB2

The Chemical Biology of DNA Damage 1st Edition by Nicholas E. Geacintov (Editor), Suse Broyde (Editor) out of 5 stars 2 ratings. ISBN ISBN Why is ISBN important. ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition of a book.

5/5(2). The Chemical Biology of DNA Damage. Editor(s): Prof. Nicholas E. Geacintov; Prof. Suse Broyde; "I believe that it will serve as a good reference book for many researchers in the field and provide a basis for research." (The British Toxicology Society, 1 May ) research interests are focused on the mechanisms of chemical.

The Chemical Biology of DNA Damage View larger image. By: Nicholas E. Geacintov and Suse Broyde. Sign Up Now. Already a Member. Book Details Book Quality: Publisher Quality Book Size: Pages ISBN Related ISBNs:Publisher: Wiley Pages: The Chemical Biology Of Dna Damage Download The Chemical Biology Of Dna Damage books, Bringing the power of biochemical analysis to toxicology, this modern reference explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or.

TY - BOOK. T1 - The Chemical Biology of DNA Damage. AU - Geacintov, Nicholas E. AU - Broyde, Suse. PY - /10/ Y1 - /10/ N2 - Bringing the power of biochemical analysis to toxicology, this modern reference explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or organismic by: The Chemical Biology of DNA Damage: Bringing the power of biochemical analysis to toxicology, this modern reference explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or organismic response.

Clearly divided into two main sections, Part 1 focuses on selected examples of important DNA lesions and their biological impact, while the. The Chemical Biology of DNA Damage. Nicholas E. Geacintov (Editor), Suse Broyde (Editor) ISBN: Jun pages. Quantity: Select type: Hardcover.

E-Book £ In Stock Hardcover £ O-Book. In Stock. £ * VAT information. Add to cart. Purchase DNA Repair Enzymes: Cell, Molecular, and Chemical Biology, Volume - 1st Edition. Print Book & E-Book. ISBNThe Chemical Biology of DNA Damage > Summary; BOOK TOOLS.

Save to My Profile; Purchase a print copy; Recommend to Your Librarian; BOOK MENU. Book Home; GET ACCESS. How to Get Online Access; FOR CONTRIBUTORS. For Authors; ABOUT THIS BOOK.

Table of Contents; Reviews; Author Biography; Recognition and Removal of Bulky DNA Lesions by the. Chapter Nine - Xenopus laevis as Model System to Study DNA Damage Response and Replication Fork Stability Vincenzo Sannino, Federica Pezzimenti, Stefania Bertora, Vincenzo Costanzo Pages Human Biology 9th Edition $ Home / Ebook / Carcinogens, DNA Damage and Cancer Risk: Mechanisms of Chemical Carcinogenesis Carcinogens, DNA Damage and Cancer Risk: Mechanisms of Chemical Carcinogenesis.

Get this from a library. The chemical biology of DNA damage. [Nicholas E Geacintov; Suse Broyde;] -- A modern reference on a key topic in biochemical toxicology that reaches out into molecular biology, molecular medicine and environmental science, The Chemical Biology of DNA Damage covers basic.

PART ONE Chemistry and Biology of DNA Lesions. 1 Introduction and Perspectives on the Chemistry and Biology of DNA Damage (Nicolas E. Geacintov and Susan Broyde). Overview of the Field. DNA Damage A Constant Threat.

DNA Damage and Disease. DNA Damage and Chemotherapeutic Applications. The Cellular DNA Damage Response (DDR). Download the eBook The Chemical Biology of DNA Damage - Nicholas E. Geacintov in PDF or EPUB format and read it directly on your mobile phone, computer or any device.

Bacterial second messenger cyclic di-AMP (c-di-AMP) is implicated in signaling DNA damage and cell wall stress through interactions with several protein receptors and a widespread ydaO-type. PART ONE Chemistry and Biology of DNA Lesions.

1 Introduction and Perspectives on the Chemistry and Biology of DNA Damage (Nicolas E. Geacintov and Susan Broyde). Overview of the Field. DNA Damage–A Constant Threat. DNA Damage and Disease.

DNA Damage and Chemotherapeutic Applications. The Cellular DNA Damage Response (DDR). Alison Hall, M. Leuwer, in Side Effects of Drugs Annual, Genotoxicity.

DNA damage by N 2 O has been studied in 84 medical staff who had had occupational exposure to N 2 O and halogenated hydrocarbons for at least 5 years [20 c].The control group consisted of 83 staff members working outside the theatre environment. DNA damage in peripheral blood leukocytes was measured, and the.

Bases in the DNA can show limited chemical stability and are susceptible to chemical alterations through various types of damage, including alkylation, oxidation, radiation, and hydrolysis. G-quadruplexes are nucleic acids secondary structures that can be formed in guanine-rich sequences. More than 30 years ago, their formation was first observed in telomeric DNA.

Since then, a number of other sequences capable of forming G-quadruplex structures. DNA, organic chemical of complex molecular structure found in all prokaryotic and eukaryotic cells.

It codes genetic information for the transmission of inherited traits. The structure of DNA was described inleading to further understanding of DNA replication and hereditary control of cellular activities.

Chemical Research in Toxicology32 (4), DOI: /stox.8b Qiao-Ying Li, Neng-Bin Xie, Jun Xiong, Bi-Feng Yuan, Yu-Qi Feng. Single-Nucleotide Resolution Analysis of 5-Hydroxymethylcytosine in DNA by Enzyme-Mediated Deamination in Combination with Sequencing. Such issues as DNA bending and DNA winding in the nucleosome particles is covered in significant details.

The nucleosome is the basic element of chromosomes and its structure and its chemical modifications are enormously important for understanding the modern issues of the biology of higher organisms (eukaryotes).The chemical biology of dna damage.

admin 0. Chemistry of DNA Damage Repair. Erin J. Heenan and Aziz Sancar, university of North Carolina School of Medicine, Chapel Hill, North Carolina. DNA repair is the elimination of covalent DNA modifications and the correction of base mismatches.